A recent study analyzing health records of tens of thousands of adults with chronic insomnia found an association between long-term prescribed melatonin use and an increased risk of heart failure. Those who took melatonin for over a year had a higher likelihood of developing heart failure within five years compared to nonusers, the American Heart Association reported on Monday.
Sleep medicine specialists and cardiologists have expressed mixed responses to the study's results. They emphasize caution, urging people and health care providers not to make immediate changes based on this preliminary data.
The study "has not yet been peer reviewed" and further research is needed to better understand the long-term effects of melatonin use, experts state.
The findings appear to contradict earlier research that suggested melatonin might provide health benefits for patients with heart failure.
The results come from a research abstract set to be presented at the American Heart Association’s Scientific Sessions, a conference focusing on cardiovascular science and medicine.
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Author's summary: Early research hints at a link between long-term melatonin use and increased heart failure risk, but experts advise against hasty conclusions pending further studies.