UTSA vs South Florida Prediction, Picks & Odds for Tonight — College Football Week 11

Prediction and Picks for UTSA vs South Florida — College Football Week 11

South Florida is expected to dominate offensively and secure a decisive victory Thursday, November 6. Experts predict the Bulls will control the game and do almost anything they want on offense, aiming to keep their AAC and CFP hopes alive.

South Florida hosts UTSA in a game the Bulls need after their recent loss to Memphis. They benefit from extra rest while UTSA arrives on a high note following a win against Tulane. The prediction favors the home team’s explosive offense.

Betting Odds and Predictions

South Florida -13.5 (-115)

Despite UTSA’s win over Tulane last week, it was not entirely convincing. The Roadrunners benefited from mistakes by Tulane, such as a fumble, missed field goal, and turnovers, which helped their victory. Underlying defensive metrics indicate UTSA struggles, with Tulane posting a 13% explosive play rate, placing them in the top 15 nationally for that week.

Author’s Summary

This analysis favors South Florida’s potent offense and suggests they will lead comfortably, despite UTSA’s recent victory being somewhat deceptive due to opponent mistakes.

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Covers.com Covers.com — 2025-11-06