The Sopranos has a nearly perfect opening title sequence, featuring Tony Soprano driving through New Jersey, accompanied by Alabama 3's "Woke Up This Morning".
However, creator David Chase initially considered a different song, by Elvis Costello, which would have explicitly stated the show's themes.
It would have been a terrible choice, according to the show's history.
Author's summary: The Sopranos almost had a disastrous main theme song.